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Asymmetric Synthesis of trans-2,5-Disubstituted Pyrrolidines from Enantiopure Homoallylic Amines. Synthesis of Pyrrolidine (−)-197B

Iodocyclization of sulfinimine-derived enantiopure homoallylic sulfonamides affords trans-2,5-disubstituted 3-iodopyrrolidines and represents valuable methodology for the asymmetric synthesis of this important heterocyclic ring system.

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Detalhes bibliográficos
Main Authors: Davis, Franklin A., Song, Minsoo, Augustine, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536609/
https://ncbi.nlm.nih.gov/pubmed/16555832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo052566h
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