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The Secretory Route of the Leaderless Protein Interleukin 1β Involves Exocytosis of Endolysosome-related Vesicles

Interleukin 1β (IL-1β), a secretory protein lacking a signal peptide, does not follow the classical endoplasmic reticulum-to-Golgi pathway of secretion. Here we provide the evidence for a “leaderless” secretory route that uses regulated exocytosis of preterminal endocytic vesicles to transport cytos...

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Библиографические подробности
Главные авторы: Andrei, Cristina, Dazzi, Cecilia, Lotti, Lavinia, Torrisi, Maria Rosaria, Chimini, Giovanna, Rubartelli, Anna
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC25302/
https://ncbi.nlm.nih.gov/pubmed/10233156
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