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Evolution, role in inflammation, and redox control of leaderless secretory proteins

Members of the interleukin (IL)-1 family are key determinants of inflammation. Despite their role as intercellular mediators, most lack the leader peptide typically required for protein secretion. This lack is a characteristic of dozens of other proteins that are actively and selectively secreted fr...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Sitia, Roberto, Rubartelli, Anna
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261794/
https://ncbi.nlm.nih.gov/pubmed/32332096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.008907
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