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Histone deacetylase inhibitors prevent exocytosis of interleukin-1β-containing secretory lysosomes: role of microtubules

A number of agents reducing interleukin-1β (IL-1β) activity are being developed as novel immunomodulatory and anti-inflammatory therapies. However, the elucidation of their molecular mechanism of action is required in the context of medical management of inflammatory diseases. Inhibitors of histone...

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Detalhes bibliográficos
Main Authors: Carta, Sonia, Tassi, Sara, Semino, Claudia, Fossati, Gianluca, Mascagni, Paolo, Dinarello, Charles A., Rubartelli, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895509/
https://ncbi.nlm.nih.gov/pubmed/16684958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-014126
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