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A new ubiquitin ligase involved in p57(KIP2) proteolysis regulates osteoblast cell differentiation
Transforming growth factor-β1 (TGF-β1) has many physiological functions and inhibits the differentiation of osteoblasts. Previously, we reported that TGF-β1 stimulation induces the degradation of p57(KIP2) in osteoblasts. p57(KIP2) proteolysis depends on the ubiquitin–proteasome pathway and SMAD-med...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529345/ https://ncbi.nlm.nih.gov/pubmed/18660753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.125 |
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