Ligand-dependent Degradation of Smad3 by a Ubiquitin Ligase Complex of ROC1 and Associated Proteins
Smads are signal mediators for the members of the transforming growth factor-β (TGF-β) superfamily. Upon phosphorylation by the TGF-β receptors, Smad3 translocates into the nucleus, recruits transcriptional coactivators and corepressors, and regulates transcription of target genes. Here, we show tha...
Sábháilte in:
| Foilsithe in: | Mol Biol Cell |
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| Príomhchruthaitheoirí: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe / Cruthaithe: |
American Society for Cell Biology
2001
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| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34595/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359933/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.5.1431 |
| Clibeanna: |
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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