Ligand-dependent Degradation of Smad3 by a Ubiquitin Ligase Complex of ROC1 and Associated Proteins

Smads are signal mediators for the members of the transforming growth factor-β (TGF-β) superfamily. Upon phosphorylation by the TGF-β receptors, Smad3 translocates into the nucleus, recruits transcriptional coactivators and corepressors, and regulates transcription of target genes. Here, we show tha...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Fukuchi, Minoru, Imamura, Takeshi, Chiba, Tomoki, Ebisawa, Takanori, Kawabata, Masahiro, Tanaka, Keiji, Miyazono, Kohei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34595/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359933/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.5.1431
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