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14-3-3η is a novel regulator of parkin ubiquitin ligase

Mutation of the parkin gene, which encodes an E3 ubiquitin-protein ligase, is the major cause of autosomal recessive juvenile parkinsonism (ARJP). Although various substrates for parkin have been identified, the mechanisms that regulate the ubiquitin ligase activity of parkin are poorly understood....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sato, Shigeto, Chiba, Tomoki, Sakata, Eri, Kato, Koichi, Mizuno, Yoshikuni, Hattori, Nobutaka, Tanaka, Keiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356342/
https://ncbi.nlm.nih.gov/pubmed/16096643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600774
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