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14-3-3η is a novel regulator of parkin ubiquitin ligase
Mutation of the parkin gene, which encodes an E3 ubiquitin-protein ligase, is the major cause of autosomal recessive juvenile parkinsonism (ARJP). Although various substrates for parkin have been identified, the mechanisms that regulate the ubiquitin ligase activity of parkin are poorly understood....
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356342/ https://ncbi.nlm.nih.gov/pubmed/16096643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600774 |
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