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Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast
A ubiquitin-like modifier, NEDD8, is covalently attached to cullin-family proteins, but its physiological role is poorly understood. Here we report that the NEDD8-modifying pathway is essential for cell viability and function of Pcu1 (cullin-1 orthologue) in fission yeast. Pcu1 assembled on SCF ubiq...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313942/ https://ncbi.nlm.nih.gov/pubmed/10880460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3475 |
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