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Replica exchange simulations of transient encounter complexes in protein–protein association

Recent paramagnetic relaxation enhancement (PRE) studies on several weakly interacting protein complexes have unequivocally demonstrated the existence of transient encounter complexes. Here, we present a computational method to study protein–protein binding by creating equilibrium ensembles that inc...

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Detalles Bibliográficos
Main Authors: Kim, Young C., Tang, Chun, Clore, G. Marius, Hummer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529066/
https://ncbi.nlm.nih.gov/pubmed/18728193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802460105
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