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Coarse-grained models for simulations of multi-protein complexes: Application to ubiquitin binding
We develop coarse-grained models and effective energy functions for simulating thermodynamic and structural properties of multi-protein complexes with relatively low binding affinity (K(d) > 1 μM) and apply them to binding of Vps27 to membrane-tethered ubiquitin. Folded protein domains are repres...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2343030/ https://ncbi.nlm.nih.gov/pubmed/18083189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.063 |
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