The solution structure of the amino-terminal domain of human DNA polymerase ε subunit B is homologous to C-domains of AAA+ proteins

DNA polymerases α, δ and ε are large multisubunit complexes that replicate the bulk of the DNA in the eukaryotic cell. In addition to the homologous catalytic subunits, these enzymes possess structurally related B subunits, characterized by a carboxyterminal calcineurin-like and an aminoproximal oli...

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Bibliographic Details
Main Authors: Nuutinen, Tarmo, Tossavainen, Helena, Fredriksson, Kai, Pirilä, Päivi, Permi, Perttu, Pospiech, Helmut, Syvaoja, Juhani E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528186/
https://ncbi.nlm.nih.gov/pubmed/18676977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn497
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