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The role of DNA polymerase activity in human non-homologous end joining
In mammalian cells, DNA double-strand breaks are repaired mainly by non-homologous end joining, which modifies and ligates two DNA ends without requiring extensive base pairing interactions for alignment. We investigated the role of DNA polymerases in DNA-PK-dependent end joining of restriction-dige...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2001
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC55831/ https://ncbi.nlm.nih.gov/pubmed/11470886 |
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