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The role of DNA polymerase activity in human non-homologous end joining

In mammalian cells, DNA double-strand breaks are repaired mainly by non-homologous end joining, which modifies and ligates two DNA ends without requiring extensive base pairing interactions for alignment. We investigated the role of DNA polymerases in DNA-PK-dependent end joining of restriction-dige...

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Detalhes bibliográficos
Main Authors: Pospiech, Helmut, Rytkönen, Anna K., Syväoja, Juhani E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55831/
https://ncbi.nlm.nih.gov/pubmed/11470886
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