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The role of DNA polymerase activity in human non-homologous end joining

In mammalian cells, DNA double-strand breaks are repaired mainly by non-homologous end joining, which modifies and ligates two DNA ends without requiring extensive base pairing interactions for alignment. We investigated the role of DNA polymerases in DNA-PK-dependent end joining of restriction-dige...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Pospiech, Helmut, Rytkönen, Anna K., Syväoja, Juhani E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11470886/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.15.3277
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