A neutralizing antibody against human DNA polymerase epsilon inhibits cellular but not SV40 DNA replication.

The contribution of human DNA polymerase epsilon to nuclear DNA replication was studied. Antibody K18 that specifically inhibits DNA polymerase activity of human DNA polymerase epsilon in vitro significantly inhibits DNA synthesis both when microinjected into nuclei of exponentially growing human fi...

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Main Authors: Pospiech, H, Kursula, I, Abdel-Aziz, W, Malkas, L, Uitto, L, Kastelli, M, Vihinen-Ranta, M, Eskelinen, S, Syväoja, J E
Formato: Artigo
Idioma:Inglês
Publicado: 1999
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC148642/
https://ncbi.nlm.nih.gov/pubmed/10481018
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