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A neutralizing antibody against human DNA polymerase epsilon inhibits cellular but not SV40 DNA replication.

The contribution of human DNA polymerase epsilon to nuclear DNA replication was studied. Antibody K18 that specifically inhibits DNA polymerase activity of human DNA polymerase epsilon in vitro significantly inhibits DNA synthesis both when microinjected into nuclei of exponentially growing human fi...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Nucleic Acids Res
Príomhchruthaitheoirí: Pospiech, H, Kursula, I, Abdel-Aziz, W, Malkas, L, Uitto, L, Kastelli, M, Vihinen-Ranta, M, Eskelinen, S, Syväoja, J E
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Oxford University Press 1999
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10481018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.19.3799
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