A neutralizing antibody against human DNA polymerase epsilon inhibits cellular but not SV40 DNA replication.

The contribution of human DNA polymerase epsilon to nuclear DNA replication was studied. Antibody K18 that specifically inhibits DNA polymerase activity of human DNA polymerase epsilon in vitro significantly inhibits DNA synthesis both when microinjected into nuclei of exponentially growing human fi...

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Bibliografske podrobnosti
Main Authors: Pospiech, H, Kursula, I, Abdel-Aziz, W, Malkas, L, Uitto, L, Kastelli, M, Vihinen-Ranta, M, Eskelinen, S, Syväoja, J E
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC148642/
https://ncbi.nlm.nih.gov/pubmed/10481018
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