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The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae

BACKGROUND: Streptococcus pneumoniae is the major cause of community-acquired pneumonia and is also associated with bronchitis, meningitis, otitis and sinusitis. The emergence and increasing prevalence of resistance to penicillin and other antibiotics has led to interest in other anti-pneumonococcal...

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Bibliographische Detailangaben
Hauptverfasser: Sohi, Maninder K., Veselkov, Dennis A., Laponogov, Ivan, Pan, Xiao-Su, Fisher, L. Mark, Sanderson, Mark R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527675/
https://ncbi.nlm.nih.gov/pubmed/18787651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003201
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