The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae

BACKGROUND: Streptococcus pneumoniae is the major cause of community-acquired pneumonia and is also associated with bronchitis, meningitis, otitis and sinusitis. The emergence and increasing prevalence of resistance to penicillin and other antibiotics has led to interest in other anti-pneumonococcal...

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Main Authors: Sohi, Maninder K., Veselkov, Dennis A., Laponogov, Ivan, Pan, Xiao-Su, Fisher, L. Mark, Sanderson, Mark R.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527675/
https://ncbi.nlm.nih.gov/pubmed/18787651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003201
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