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A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation
The oncogenic kinase Bcr-Abl is thought to cause chronic myelogenous leukemia (CML) by altering the transcription of specific genes with growth- and survival-promoting functions. Recently Bcr-Abl has also been shown to activate an important regulator of protein synthesis, the mammalian target of rap...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527622/ https://ncbi.nlm.nih.gov/pubmed/16936779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209901 |
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