Mutation in the polyomavirus genome that activates the properties of large T associated with neoplastic transformation.

We have constructed a polyomavirus mutant genome which exhibits an increased immortalization potential when transfected into primary rat embryo fibroblasts. The mutation is a 30-base-pair deletion (nucleotides 1367 through 1396) that inactivates the transforming potential of middle T but activates s...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Asselin, C, Vass-Marengo, J, Bastin, M
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3001342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.57.1.165-172.1986
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