Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization.
To clarify the relationship between the various activities of the polyomavirus large T antigen and the contribution of this oncogene to neoplastic transformation, we constructed a series of mutants with small deletions or single-amino-acid substitutions in two separate regions of the protein. These...
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| Publicado no: | J Virol |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240580/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2016761/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2308-2313.1991 |
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