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Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization.

To clarify the relationship between the various activities of the polyomavirus large T antigen and the contribution of this oncogene to neoplastic transformation, we constructed a series of mutants with small deletions or single-amino-acid substitutions in two separate regions of the protein. These...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Larose, A, Dyson, N, Sullivan, M, Harlow, E, Bastin, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC240580/
https://ncbi.nlm.nih.gov/pubmed/2016761
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