Polyomavirus large T mutants affected in retinoblastoma protein binding are defective in immortalization.

To clarify the relationship between the various activities of the polyomavirus large T antigen and the contribution of this oncogene to neoplastic transformation, we constructed a series of mutants with small deletions or single-amino-acid substitutions in two separate regions of the protein. These...

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Xehetasun bibliografikoak

Argitaratua izan da:	J Virol
Egile Nagusiak:	Larose, A, Dyson, N, Sullivan, M, Harlow, E, Bastin, M
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1991
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240580/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2016761/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.5.2308-2313.1991
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