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Synthesis and Mutagenesis of the Butadiene-derived N3 2′-deoxyuridine adducts
1,3-Butadiene is a known carcinogen and mutagen that acts through a variety of metabolic intermediates that react with DNA, forming stable and unstable lesions on dG, dA, dC and dT. The N3 2′-deoxyuridine adducts are a highly stable, stereoisomeric mixture of adducts derived from the reaction of cyt...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2526974/ https://ncbi.nlm.nih.gov/pubmed/16841966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060016o |
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