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RACK1 Regulates Directional Cell Migration by Acting on Gβγ at the Interface with Its Effectors PLCβ and PI3Kγ

Migration of cells up the chemoattractant gradients is mediated by the binding of chemoattractants to G protein–coupled receptors and activation of a network of coordinated excitatory and inhibitory signals. Although the excitatory process has been well studied, the molecular nature of the inhibitor...

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Detalhes bibliográficos
Main Authors: Chen, Songhai, Lin, Fang, Shin, Myung Eun, Wang, Fei, Shen, Lixin, Hamm, Heidi E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526680/
https://ncbi.nlm.nih.gov/pubmed/18596232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-04-0433
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