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VEGFR1 promotes cell migration and proliferation through PLCγ and PI3K pathways

The ability to control vascular endothelial growth factor (VEGF) signaling offers promising therapeutic potential for vascular diseases and cancer. Despite this promise, VEGF-targeted therapies are not clinically effective for many pathologies, such as breast cancer. VEGFR1 has recently emerged as a...

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Detalhes bibliográficos
Publicado no:NPJ Syst Biol Appl
Main Authors: Weddell, Jared C., Chen, Si, Imoukhuede, P. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736688/
https://ncbi.nlm.nih.gov/pubmed/29263797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-017-0037-9
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