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Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs
RNA interference (RNAi) is a cellular process regulating gene expression and participating in innate defense in many organisms. RNAi has also been utilized as a tool to query gene function and is being developed as a therapeutic strategy for several diseases. Synthetic small interfering (siRNAs) or...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
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Cold Spring Harbor Laboratory Press
2008
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525944/ https://ncbi.nlm.nih.gov/pubmed/18697922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1062908 |
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