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MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis

Two eukaryotic pathways for processing double-strand breaks (DSBs) as crossovers have been described, one dependent on the MutL homologs Mlh1 and Mlh3, and the other on the structure-specific endonuclease Mus81. Mammalian MUS81 has been implicated in maintenance of genomic stability in somatic cells...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Holloway, J. Kim, Booth, James, Edelmann, Winfried, McGowan, Clare H., Cohen, Paula E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525838/
https://ncbi.nlm.nih.gov/pubmed/18787696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000186
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