The Mus81/Mms4 endonuclease acts independently of double-Holliday junction resolution to promote a distinct subset of crossovers during meiosis in budding yeast.

Current models for meiotic recombination require that crossovers derive from the resolution of a double-Holliday junction (dHJ) intermediate. In prokaryotes, enzymes responsible for HJ resolution are well characterized but the identification of a eukaryotic nuclear HJ resolvase has been elusive. Ind...

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Autores principales: de los Santos, Teresa, Hunter, Neil, Lee, Cindy, Larkin, Brittany, Loidl, Josef, Hollingsworth, Nancy M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462551/
https://ncbi.nlm.nih.gov/pubmed/12750322
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