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Indiscriminate Binding by OMP Decarboxylase of UMP Derivatives with Bulky Anionic C(6)-Substituents

OMP decarboxylase appears to act upon its substrate without the intervention of metals or other cofactors and without the formation of covalent bonds between the enzyme and the substrate. Crystallographic information indicates that substrate binding forces the substrate’s scissile carboxylate group...

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Bibliografiska uppgifter
Huvudupphovsmän: Lewis, Charles A., Wolfenden, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525794/
https://ncbi.nlm.nih.gov/pubmed/17967036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700796t
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