Neural stem cell transplantation can ameliorate the phenotype of a mouse model of spinal muscular atrophy

Spinal muscular atrophy (SMA), a motor neuron disease (MND) and one of the most common genetic causes of infant mortality, currently has no cure. Patients with SMA exhibit muscle weakness and hypotonia. Stem cell transplantation is a potential therapeutic strategy for SMA and other MNDs. In this stu...

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Главные авторы: Corti, Stefania, Nizzardo, Monica, Nardini, Martina, Donadoni, Chiara, Salani, Sabrina, Ronchi, Dario, Saladino, Francesca, Bordoni, Andreina, Fortunato, Francesco, Del Bo, Roberto, Papadimitriou, Dimitra, Locatelli, Federica, Menozzi, Giorgia, Strazzer, Sandra, Bresolin, Nereo, Comi, Giacomo P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2008
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525699/
https://ncbi.nlm.nih.gov/pubmed/18769634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35432
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