Neural stem cell transplantation can ameliorate the phenotype of a mouse model of spinal muscular atrophy

Spinal muscular atrophy (SMA), a motor neuron disease (MND) and one of the most common genetic causes of infant mortality, currently has no cure. Patients with SMA exhibit muscle weakness and hypotonia. Stem cell transplantation is a potential therapeutic strategy for SMA and other MNDs. In this stu...

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Detalhes bibliográficos
Main Authors: Corti, Stefania, Nizzardo, Monica, Nardini, Martina, Donadoni, Chiara, Salani, Sabrina, Ronchi, Dario, Saladino, Francesca, Bordoni, Andreina, Fortunato, Francesco, Del Bo, Roberto, Papadimitriou, Dimitra, Locatelli, Federica, Menozzi, Giorgia, Strazzer, Sandra, Bresolin, Nereo, Comi, Giacomo P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525699/
https://ncbi.nlm.nih.gov/pubmed/18769634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35432
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