Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

Embryonic stem cells (ESCs) could potentially compensate for the lack of blood platelets available for use in transfusions. Here, we describe a new method for generating mouse ESC-derived platelets (ESPs) that can contribute to hemostasis in vivo. Flow cytometric sorting of cells from embryoid bodie...

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Huvudupphovsmän: Nishikii, Hidekazu, Eto, Koji, Tamura, Noriko, Hattori, Koichi, Heissig, Beate, Kanaji, Taisuke, Sawaguchi, Akira, Goto, Shinya, Ware, Jerry, Nakauchi, Hiromitsu
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2008
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525582/
https://ncbi.nlm.nih.gov/pubmed/18663123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071482
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