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Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127(pos) Depletion, Treg Expansion, and Treg Cryopreservation
BACKGROUND: Treg based immunotherapy is of great interest to facilitate tolerance in autoimmunity and transplantation. For clinical trials, it is essential to have a clinical grade Treg isolation protocol in accordance with Good Manufacturing Practice (GMP) guidelines. To obtain sufficient Treg for...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2522271/ https://ncbi.nlm.nih.gov/pubmed/18776930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003161 |
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