Fluorine-Substituted Cyclofenil Derivatives as Estrogen Receptor Ligands: Synthesis and Structure-Affinity Relationship Study of Potential PET Agents for Imaging Estrogen Receptors in Breast Cancer

In a search for estrogen receptor (ER) ligands to be radiolabeled with fluorine-18 for imaging of ER-positive breast tumors with positron emission tomography (PET), we investigated cyclofenil analogs substituted at the C3 or C4 position of the cyclohexyl group. McMurry coupling of 4,4′-dihydroxybenz...

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Hlavní autoři: Seo, Jai Woong, Comninos, John S., Chi, Dae Yoon, Kim, Dong Wook, Carlson, Kathryn E., Katzenellenbogen, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522267/
https://ncbi.nlm.nih.gov/pubmed/16610793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0512037
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