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Negative Regulation of Cdc18 DNA Replication Protein by Cdc2

Fission yeast Cdc18, a homologue of Cdc6 in budding yeast and metazoans, is periodically expressed during the S phase and required for activation of replication origins. Cdc18 overexpression induces DNA rereplication without mitosis, as does elimination of Cdc2-Cdc13 kinase during G(2) phase. These...

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Detalhes bibliográficos
Main Authors: Lopez-Girona, Antonia, Mondesert, Odile, Leatherwood, Janet, Russell, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25219/
https://ncbi.nlm.nih.gov/pubmed/9436991
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