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Expression of Cdc18/Cdc6 and Cdt1 during G(2) phase induces initiation of DNA replication

Cdc18/Cdc6 and Cdt1 are essential initiation factors for DNA replication. In this paper we show that expression of Cdc18 in fission yeast G(2) cells is sufficient to override the controls that ensure one S phase per cell cycle. Cdc18 expression in G(2) induces DNA synthesis by re-firing replication...

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Bibliografske podrobnosti
Main Authors: Yanow, Stephanie K., Lygerou, Zoi, Nurse, Paul
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC125588/
https://ncbi.nlm.nih.gov/pubmed/11532929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4648
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