Expression of Cdc18/Cdc6 and Cdt1 during G(2) phase induces initiation of DNA replication
Cdc18/Cdc6 and Cdt1 are essential initiation factors for DNA replication. In this paper we show that expression of Cdc18 in fission yeast G(2) cells is sufficient to override the controls that ensure one S phase per cell cycle. Cdc18 expression in G(2) induces DNA synthesis by re-firing replication...
Guardat en:
| Publicat a: | EMBO J |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11532929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.17.4648 |
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