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p53-Targeted LSD1 Functions in Repression of Chromatin Structure and Transcription In Vivo
Despite years of study focused on the tumor suppressor p53, little is understood about its functions in normal, differentiated cells. We found that p53 directly interacts with lysine-specific demethylase 1 (LSD1) to alter chromatin structure and confer developmental repression of the tumor marker al...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519740/ https://ncbi.nlm.nih.gov/pubmed/18573881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00287-08 |
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