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Hypoxia induces a novel signature of chromatin modifications and global repression of transcription

Tumor cells respond to the harsh hypoxic microenvironment, in part, by transcriptional regulation of specific target genes. We found that hypoxia-mediated activation of selected genes occurs amidst widespread repression of transcription that is neither cell type-specific nor HIF-1-dependent. Despite...

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Bibliografski detalji
Glavni autori: Johnson, Amber Buescher, Denko, Nicholas, Barton, Michelle Craig
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346607/
https://ncbi.nlm.nih.gov/pubmed/18294659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2008.01.001
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