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Hypoxia induces a novel signature of chromatin modifications and global repression of transcription
Tumor cells respond to the harsh hypoxic microenvironment, in part, by transcriptional regulation of specific target genes. We found that hypoxia-mediated activation of selected genes occurs amidst widespread repression of transcription that is neither cell type-specific nor HIF-1-dependent. Despite...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2008
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2346607/ https://ncbi.nlm.nih.gov/pubmed/18294659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2008.01.001 |
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