Structure of Natural Killer Receptor 2B4 Bound to CD48 Reveals Basis for Heterophilic Recognition in Signaling Lymphocyte Activation Molecule Family

Natural killer (NK) cells eliminate virally infected and tumor cells. Among the receptors regulating NK cell function is 2B4 (CD244), a member of the signaling lymphocyte-activation molecule (SLAM) family that binds CD48. 2B4 is the only heterophilic receptor of the SLAM family, whose other members,...

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Hauptverfasser: Velikovsky, C. Alejandro, Deng, Lu, Chlewicki, Lukasz K., Fernández, Marisa M., Kumar, Vinay, Mariuzza, Roy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519619/
https://ncbi.nlm.nih.gov/pubmed/17950006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.08.019
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