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Structure of Natural Killer Cell Receptor KLRG1 Bound to E-Cadherin Reveals Basis for MHC-Independent Missing Self Recognition

The cytolytic activity of natural killer (NK) cells is regulated by inhibitory receptors that detect the absence of self molecules on target cells. Structural studies of missing self recognition have focused on NK receptors that bind MHC. However, NK cells also possess inhibitory receptors specific...

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Détails bibliographiques
Auteurs principaux: Li, Yili, Hofmann, Maike, Wang, Qian, Teng, Leslie, Chlewicki, Lukasz K., Pircher, Hanspeter, Mariuzza, Roy A
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030123/
https://ncbi.nlm.nih.gov/pubmed/19604491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.04.019
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