Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes

We previously showed that the 12/15-lipoxygenase (12/15-LO) pathway of arachidonate acid metabolism is involved in multiple events related to diabetic nephropathy (DN), including glomerular hypertrophy and extracellular matrix deposition (Kang SW, Adler SG, Nast CC, LaPage J, Gu JL, Nadler JL, Natar...

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Autores principales: Yuan, Hang, Lanting, Linda, Xu, Zhong-Gao, Li, Shu-Lian, Swiderski, Piotr, Putta, Sumanth, Jonnalagadda, Mahesh, Kato, Mitsuo, Natarajan, Rama
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2008
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519183/
https://ncbi.nlm.nih.gov/pubmed/18562637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90268.2008
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