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Structure activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors

Necroptosis is a regulated caspase-independent cell death pathway resulting in morphology reminiscent of passive non-regulated necrosis. Several diverse structure classes of necroptosis inhibitors have been reported to date, including a series of [1,2,3]thiadiazole benzylamide derivatives. However,...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Teng, Xin, Keys, Heather, Yuan, Junying, Degterev, Alexei, Cuny, Gregory D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519155/
https://ncbi.nlm.nih.gov/pubmed/18467094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.04.048
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