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Necroptosis, a Novel Form of Caspase-Independent Cell Death, Contributes to Neuronal Damage in a Retinal Ischemia-Reperfusion Injury Model

Necroptosis is programmed necrosis triggered by death receptor signaling. We investigated whether necroptosis contributes to neuronal damage and functional impairment in a model of retinal ischemia. Methods: Sprague-Dawley rats were subjected to raised intraocular pressure for 45 min and received in...

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Bibliografiske detaljer
Udgivet i:J Neurosci Res
Main Authors: Rosenbaum, Daniel M., Degterev, Alexei, David, Joel, Rosenbaum, Pearl S., Roth, Steven, Grotta, James C., Cuny, Gregory D., Yuan, Junying, Savitz, Sean I.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713513/
https://ncbi.nlm.nih.gov/pubmed/20025059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22314
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