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Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1
Necrotic cell death is prevalent in many different pathologic disease states and in traumatic injury. Necroptosis is a form of necrosis that stems from specific signaling pathways with the key regulator being RIP1, a serine/threonine kinase. Specific inhibitors of RIP1, termed necrostatins, are pote...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3398245/ https://ncbi.nlm.nih.gov/pubmed/22658960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.05.019 |
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