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Rapid tolerization of virus-activated tumor-specific CD8(+) T cells in prostate tumors of TRAMP mice
To study T cell responses to tumors in an autochthonous model, we expressed a CD8 T cell epitope SIYRYYGL (SIY) in the prostate of transgenic adenocarcinoma (TRAMP) mice (referred to as TRP-SIY), which spontaneously develop prostate cancer. Naïve SIY-specific CD8 T cells adoptively transferred into...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519043/ https://ncbi.nlm.nih.gov/pubmed/18723683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805599105 |
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