Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A

Previous studies showed that Fanconi anemia (FA) murine stem cells have defective reconstitution after bone marrow (BM) transplantation. The mechanism underlying this defect is not known. Here, we report defective homing of FA patient BM progenitors transplanted into mouse models. Using cells from p...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Zhang, Xiaoling, Shang, Xun, Guo, Fukun, Murphy, Kim, Kirby, Michelle, Kelly, Patrick, Reeves, Lilith, Smith, Franklin O., Williams, David A., Zheng, Yi, Pang, Qishen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518878/
https://ncbi.nlm.nih.gov/pubmed/18565850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-147090
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi