Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A

Previous studies showed that Fanconi anemia (FA) murine stem cells have defective reconstitution after bone marrow (BM) transplantation. The mechanism underlying this defect is not known. Here, we report defective homing of FA patient BM progenitors transplanted into mouse models. Using cells from p...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Xiaoling, Shang, Xun, Guo, Fukun, Murphy, Kim, Kirby, Michelle, Kelly, Patrick, Reeves, Lilith, Smith, Franklin O., Williams, David A., Zheng, Yi, Pang, Qishen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2008
Schlagworte:
Hematopoiesis and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518878/
https://ncbi.nlm.nih.gov/pubmed/18565850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-147090
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